Liothyronine is a synthetic thyroid hormone, available on prescription. It consists of the L-isomers of the natural thyroid hormone triiodothyronine (T3). Thyroid hormones stimulate basal metabolism and play an important role in cellular functioning, including in the metabolism of proteins, fats and carbohydrates. Lyotyronin sodium is used in medicine for the treatment of hypothyroidism, a disease in which the thyroid gland does not produce enough hormones.
In 1891, the first drug was created, which included T3 – thyroid extract. This extract was used to treat patients with myxedema (a skin disease associated with hypothyroidism). Natural thyroid extract contains therapeutically active levels of thyroid hormones T3 and T4. Since its inception and Liothyronine (T3) for more than 60 years, the substance has been widely used in medical practice. In the 1950s, however, these drugs are gradually beginning to give way to new synthetic drugs of the thyroid gland, namely, drugs of sodium lyotyronine and levothyroxine sodium, having similar dosage and efficacy, and more satisfying the needs of consumers than extracts extracted from animals. Although lithotronin sodium and levothyroxine sodium are still widely available in the United States and abroad, lithotronin retains a much smaller share of the world market for thyroid drugs. However, given the more powerful and fast-acting effect, lyotyronin sodium remains a popular drug for the thyroid gland among bodybuilders and athletes. Cytomel is the most well-known brand name in the US, where it is currently manufactured by King Pharmaceuticals.
T3: Bodybuilding Fat Burner- Thyroid Hormone: my experience and side effects
Side effects of Lyotyronin
Side effects are usually associated with overdose, and may include headache, irritability, nervousness, excessive sweating, irregular heartbeat, increased intestinal motility, or menstrual irregularities. Overdose can also cause shock, and aggravate or cause angina pectoris or congestive heart failure. Chronic overdose of sodium lyoteronin is accompanied by symptoms, usually associated with hyperthyroidism or overproduction of natural thyroid hormones in the body. If side effects of an overdose occur, the dose should be immediately reduced or the use of sodium lyrotonin completely discontinued. A severe overdose can be life threatening. Inside the package of all thyroid hormones, the following warning is given: “Drugs with thyroid hormone activity, alone or in combination with other therapeutic drugs, have been used in the past to treat obesity. For patients with euthyroid syndrome, doses in the range of daily hormonal needs are ineffective in order to reduce weight. Higher doses can cause serious or even life-threatening manifestations of toxicity, especially in combination with sympathomimetic amines, which have an anorexic effect.
Application of Lyotyronine
For the treatment of mild hypothyroidism, the typical recommended initial dose is 25 mcg per day. Then the daily dosage can be increased by no more than 25 micrograms every 1-2 weeks. The established maintenance dose is usually 25-75 μg per day. It is recommended to use the drug once a day. Although lyotyronine sodium acts rapidly, the effects of its use can be observed in the human body for several days after discontinuation of use. Among bodybuilders and athletes, lyotyronin sodium is used to accelerate fat loss at doses of 25 mcg per day. This dose can be increased by 25 mcg every 4-7 days, but not more than 75 mcg per day. The purpose of this application is to slowly accumulate the drug, allowing the body to adapt to an increase in the level of thyroid hormones, avoiding sudden changes that can cause side effects. Lytryronin sodium is usually taken no more than 6 weeks, with the treatment can not be abruptly terminated. The discontinuation of the use of the drug should be as gradual as its initiation. It is usually recommended to reduce the dose by 25 mcg every 4-7 days. This is necessary for the body to reconstruct the production of its endogenous hormones after the end of therapy, and also to avoid the occurrence of side effects.